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MP-SPR for antibody characterization

MP-SPR is a sensitive platform to determine antibody – antigen interactions. Label-free interactions are measured in real-time, revealing affinity and kinetics of the binding. MP-SPR with LayerSolver™ provides insight into the conformation and orientation of the antibodies. With PureKinetics™, bulk effect can be distinguished from binding and high precision results are obtained.

Interaction measurements can be performed in diverse liquids including complex liquids such as serum or saliva. MP-SPR instruments can also handle organic solvents.


See reasons to choose MP-SPR for antibody characterization:

  • Label-free affinity and kinetics
  • KineticTitration for faster measurements
  • Low total cost of ownership
  • Conformation changes
  • Crude samples (100% serum)
  • Easy ex-situ preparation of own sensor surfaces 

See key questions about antibody that MP-SPR can answer:

  • What is antibody X affinity and kinetics to antigen Z?
  • What is the best antibody for successful immunoassay?
  • How fast is molecule X association and dissociation kinetics to molecule Y?
  • Which monoclonal antibody has highest affinity?
  • How much is the real binding without bulk effect?

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